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Insulinotropic actions of nateglinide in type 2 diabetic patients and effects on dipeptidyl peptidase-IV activity and glucose-dependent insulinotropic polypeptide degradation

机译：那格列奈对2型糖尿病患者的促胰岛素作用及其对二肽基肽酶IV活性和葡萄糖依赖性促胰岛素多肽降解的影响

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Background: Nateglinide restores early-phase insulin secretion to feeding and reduces postprandial hyperglycaemia in type 2 diabetes. This study evaluated the effects of nateglinide on dipeptidyl peptidase-IV (DPP-IV) activity and glucose-dependent insulinotropic polypeptide (GIP) degradation

机译：背景：那格列奈可恢复喂养初期的胰岛素分泌并减少2型糖尿病的餐后高血糖。这项研究评估了那格列奈对二肽基肽酶IV（DPP-IV）活性和葡萄糖依赖性促胰岛素多肽（GIP）降解的影响

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作者
McKillop, A.M.; Duffy, N.A.; Green, Brian; Patterson, S.; O'Harte, F.P.M.; Bell, Patrick M; Flatt, P.R.; Lindsay, John;
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年度 2009
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正文语种 eng
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专利

1. Improved pancreatic beta-cell function in type 2 diabetic patients after lifestyle-induced weight loss is related to glucose-dependent insulinotropic polypeptide. [J] . Solomon TP, Haus JM, Kelly KR, Diabetes care . 2010,第7期

机译：生活方式导致的体重减轻后，2型糖尿病患者的胰岛β细胞功能改善与葡萄糖依赖性促胰岛素多肽有关。
2. Degradation, cyclic adenosine monophosphate production, insulin secretion, and glycemic effects of two novel N-terminal Ala2-substituted analogs of glucose-dependent insulinotropic polypeptide with preserved biological activity in vivo. [J] . Gault VA, OHarte FP, Harriott P, Metabolism: Clinical and Experimental . 2003,第6期

机译：葡萄糖依赖性促胰岛素多肽的两个新型N末端Ala2取代的类似物的降解，环状腺苷单磷酸的产生，胰岛素分泌和血糖效应，在体内具有保留的生物学活性。
3. Effects of Pioglitazone on Glucose-Dependent Insulinotropic Polypeptide-Mediated Insulin Secretion and Adipocyte Receptor Expression in Patients With Type 2 Diabetes [J] . William G. Tharp, Dhananjay Gupta, Olga Sideleva, Diabetes . 2020,第2期

机译：吡格列酮对2型糖尿病患者血糖依赖性胰岛素多肽介导的胰岛素分泌和脂肪细胞受体表达的影响
4. Effects of hyperglycemia on variability of RR, QT and corrected QT intervals in Type 1 diabetic patients [C] . Nguyen, LinhLan, Su, Steven, Nguyen, Hung T. Annual Conference of Japanese Society for Medical and Biological Engineering;Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2013

机译：高血糖对1型糖尿病患者RR，QT和校正QT间期变异性的影响
5. Regulation of glucose-dependent insulinotropic polypeptide (GIP) receptor expression in the pancreatic beta-cell. [D] . Lynn, Francis Christopher. 2003

机译：胰岛β细胞中葡萄糖依赖性促胰岛素多肽（GIP）受体表达的调节。
6. Improved Pancreatic β-Cell Function in Type 2 Diabetic Patients After Lifestyle-Induced Weight Loss Is Related to Glucose-Dependent Insulinotropic Polypeptide [O] . Thomas P.J. Solomon, Jacob M. Haus, Karen R. Kelly, 2010

机译：生活方式导致的体重减轻后2型糖尿病患者胰岛β细胞功能的改善与葡萄糖依赖的促胰岛素多肽有关
7. The effects of glucose-dependent insulinotropic polypeptide infused at physiological concentrations in normal subjects and Type 2 (non-insulin-dependent) diabetic patients on glucose tolerance and B-cell secretion [O] . I. R. Jones, D. R. Owens, A. J. Moody, 1987

机译：葡萄糖依赖性胰岛素多肽在正常受试者和2型（非胰岛素依赖性）糖尿病患者血糖耐受性和B细胞分泌中的影响

Insulinotropic actions of nateglinide in type 2 diabetic patients and effects on dipeptidyl peptidase-IV activity and glucose-dependent insulinotropic polypeptide degradation

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